LIQUID OR MONOCAPA CYTOLOGY: Better diagnosis of cervical cancer.

The liquid cytology improves diagnosis of cervical cancer.

The “cytology” fundamental part of the gynecological examination, is the method of choice in screening for early detection of cervical cancer or its precursor lesions. Cytology testing should happen once people begin to have sexual relationships.
Cytology envolves taking a sample of cells from the three most representative areas of the cervix, the surface (exocervix), the inlet (endocervix) and the innermost portion of the vagina (vaginal fornix), which is called triple take. Classically, extended the sample into a glass slide (slide), it is sent to the pathology laboratory for examination. In the tests performed in the laboratory is what is properly called “Pap Test”, although this name has become popular in many ways to name the entire test including sampling.

Liquid cytology is a technique in which, after collecting the sample in a similar way as is done conventionally, instead of extending directly onto the slide glass, is introduced in a little container with liquid preservative. In the laboratory technique differs from the usual cytology in that, after a series of processes, the cells are filtered and transferred to slides in a thin layer whose thickness has only one level representative cell (monolayer) of the entire sample. This makes the examination of the specimen easier than conventional Pap, where the spread of it is made from crudest form, so that the layer of cells is irregular and sometimes very thick, which makes it difficult to see the cells individually or with such precision.

Apart from the obvious advantages enjoyed the test is easy to carry out. Additionally that there are always cells in the small boat to, if necessary, to repeat the extended, or apply other laboratory techniques to deepen the diagnosis, such as the detection and typing of human papillomavirus (HPV). This solves a case without the patient having to repeat the sampling, which is very stressful for the patient.

Another advantage is that cells undergo less distortion by pressure to undergo in conventional extensions, and leukocytes, mucus, and other substances such as remains of vaginal medication interfering reading the samples are removed.

With advances in clarity, reliability and ease provided by the system liquid cytology versus conventional cytology, it seems clear that detection of cervical cancer is improved.

So three years ago, the Food and Drug Administration (FDA) showed that the new method of making the Pap test was significantly more effective than conventional cytology in detecting cervical cancer or precursor lesions of the cervix.